Wegovy Tablet

Wegovy Tablets are a prescription-only oral treatment for weight management. They contain semaglutide, a medicine belonging to the GLP-1 receptor agonist class and provide an alternative for people who would prefer a tablet rather than an injection.

Taken once daily, they are prescribed alongside dietary changes and increased physical activity to help eligible adults manage their weight.

The active ingredient in Wegovy Tablets, semaglutide, acts on the body's appetite-regulating system by activating GLP-1 receptors.

This helps reduce hunger, control cravings and increase feelings of fullness, so you may naturally eat smaller portions and consume fewer calories. Over time, this can contribute to weight loss when combined with healthy eating and regular physical activity.

Wegovy Tablets are taken once daily, preferably at the same time each morning. They must be swallowed whole on an empty stomach with a small amount of plain water, followed by a wait of at least 30 minutes before eating, drinking or taking other oral medicines.

Treatment begins at 1.5 mg daily, with the dose gradually increased after at least one month at each strength, depending on your response and tolerability.

If you miss a dose, skip it and take your next tablet the following day. Do not take two doses to make up for a missed tablet.

The OASIS 4 clinical trial found that adults taking oral semaglutide 25 mg daily achieved an average 13.6% reduction in body weight after 64 weeks, compared with 2.2% in the placebo group. All participants also received dietary and physical activity guidance.

These findings demonstrate the potential of oral semaglutide for weight management, although individual results vary and weight loss is not guaranteed.

Wegovy Tablets can cause side effects, particularly during the first few months as your body adjusts to treatment. Digestive symptoms are the most common and often improve over time.

Common side effects include:

• Nausea, vomiting, diarrhoea and constipation
• Stomach discomfort, bloating and indigestion
• Headaches, dizziness and tiredness

How can I manage side effects?

Try eating smaller portions, avoiding heavy or fatty meals and drinking enough fluids throughout the day. Contact your prescriber if symptoms persist or interfere with daily activities.

When should I seek medical help?

Stop taking Wegovy and seek urgent medical attention if you develop severe, persistent abdominal pain, particularly if it spreads to your back. Sudden loss of vision also requires urgent assessment. Seek emergency help for breathing difficulties or swelling of your face, lips or throat.

Repeated vomiting or diarrhoea can lead to dehydration. Seek medical advice promptly if you cannot keep fluids down.

For a full list of possible side effects and precautions, refer to the Patient Information Leaflet supplied with your tablets.

Wegovy Tablets may be prescribed to adults who meet the following weight management criteria:

• BMI of 30 or above, indicating obesity.
• BMI of 27 or above, alongside at least one weight-related health condition, such as high blood pressure, type 2 diabetes or high cholesterol.

People from certain ethnic backgrounds may be considered at lower BMI thresholds in line with relevant clinical guidance.

Eligibility is not determined by BMI alone. Your prescriber will consider your medical history, current medications and overall health before deciding whether Wegovy Tablets are suitable for you.

Wegovy Tablets are not suitable for everyone. You should not take them if you:

• Are allergic to semaglutide or any of the tablet's ingredients.
• Are pregnant, planning to become pregnant or breastfeeding.
• Are already using another medicine containing semaglutide or another GLP-1 receptor agonist.

Speak to your prescriber before starting treatment if you have:

• Previously experienced pancreatitis.
• Severe stomach or digestive problems, including gastroparesis.
• Diabetic eye disease (retinopathy).
• Kidney problems or other significant medical conditions.

If you're planning a pregnancy, semaglutide should be stopped at least two months beforehand. Your prescriber will assess your medical history and current medicines to determine whether treatment is appropriate.

Wegovy Tablets may be used for ongoing weight management, provided treatment continues to be effective, suitable and well tolerated. There is no fixed maximum treatment duration.

Your prescriber will assess your progress through regular reviews, considering your weight loss, overall health and any side effects.

Weight regain can occur after stopping semaglutide, so maintaining healthy eating habits and physical activity remains important, whether you continue treatment or not.