ED treatment for greater confidence
Explore discreet erectile dysfunction care with confidential clinical assessment, personalised treatment options and professional support, all from the comfort of home.
Private consultation • No obligation • Discreet UK delivery
GPhC Registered
UK licensed medication
Clinician reviewed
Fast delivery
Ongoing support
GPhC Registered
UK licensed medication
Clinician reviewed
Qualified Clinicians
Fast delivery
Ongoing support
Explore Your Treatment Options
Explore our erectile dysfunction treatment options. Each treatment has different benefits and considerations, and suitability is determined through a confidential clinical assessment.
Sildenafil
Tadalafil
Compare treatments
Which treatment is right for you?
Compare the key differences between erectile dysfunction treatments. Your prescriber will assess your individual circumstances and help determine which option, if any, is appropriate for you.
| Treatment | Sildenafil | Tadalafil |
|---|---|---|
| Medicine type | PDE5 inhibitor | PDE5 inhibitor |
| When to take | Around 1 hour before sex | At least 30 minutes before sex* |
| How long it can work | Up to 4 hours | Up to 36 hours |
| Food | Food, particularly a heavy meal, may delay how quickly it works | Can be taken with or without food |
| Sexual stimulation needed | Yes | Yes |
| Available strengths | 25 mg, 50 mg, 100 mg | 2.5 mg, 5 mg, 10 mg, 20 mg |
| Actions | Learn more Get Started | Learn more Get Started |
*Timing depends on the prescribed tadalafil regimen. These durations describe the period during which treatment may help you achieve an erection with sexual stimulation, not a continuous erection.
How It Works
Complete your assessment online and receive discreet treatment if prescribed, with professional support throughout.
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Tell us about yourself
Complete a confidential online assessment covering your ED symptoms, medical history, current medications and general health.
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Your clinical review
A qualified UK prescriber reviews your assessment to determine whether treatment is suitable and which option may be appropriate. We’ll contact you if further information is needed.
03
Receive treatment
If prescribed, your medication is dispensed by PillSuite and delivered to your chosen address in plain, discreet packaging.
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Ongoing support
Our pharmacy team is here to answer questions about your medication, side effects or treatment progress, with further clinical review when needed.
Check if erectile dysfunction treatment is right for you
Understanding Erectile Dysfunction Treatment
Erectile dysfunction (ED) is when you regularly have difficulty getting or keeping an erection firm enough for sex. It can happen for several reasons, including physical health, emotional wellbeing and lifestyle factors. Understanding what may be causing it is an important first step towards finding the right support.
Erectile dysfunction (ED) can have several causes, and sometimes a combination of physical and psychological factors.
Physical causes include high blood pressure, diabetes, high cholesterol and conditions affecting blood circulation. Certain medications, smoking, excessive alcohol consumption and a lack of physical activity can also contribute.
Stress, anxiety, depression and relationship difficulties may affect erections too. Sometimes, worrying about sexual performance can make the problem worse.
Understanding the possible cause is important, as ED can occasionally be an early sign of an underlying health condition.
Erectile dysfunction can often be treated, although the most suitable approach depends on what's causing it and your overall health.
Prescription medicines such as sildenafil and tadalafil can help improve blood flow to the penis, making it easier to get and maintain an erection when sexually aroused. These medicines do not cause an erection automatically, so sexual stimulation is still needed.
Lifestyle changes, including regular exercise, stopping smoking, reducing alcohol intake and managing stress, may also help improve erectile function.
If an underlying health condition is contributing to ED, addressing it is an important part of treatment. Your prescriber will assess your medical history and current medications before deciding whether treatment is suitable for you.
Sildenafil and tadalafil are commonly prescribed treatments for erectile dysfunction. Both work by improving blood flow to the penis, but they differ in how long their effects last and how they are taken.
Sildenafil is usually taken around one hour before sex and can work for up to four hours. Tadalafil can work for up to 36 hours, offering greater flexibility around timing. A lower-dose daily tadalafil option may also be suitable for some people.
The right treatment depends on your health, current medications, personal preferences and how often you expect to use it. Your prescriber will assess these factors before deciding which option, if any, is appropriate for you.
If you regularly experience difficulty getting or maintaining an erection, it's worth speaking to your GP, particularly if the problem is new, persistent or getting worse.
Erectile dysfunction can sometimes be an early sign of an underlying health condition, such as diabetes, high blood pressure or cardiovascular disease. Your GP can assess possible causes, review your medications and arrange further checks if needed.
You should also seek medical advice if you experience ED alongside other symptoms, such as reduced sexual desire, pain or changes in your erections.
Even if you're considering treatment through PillSuite, a GP review can help identify and address any underlying health concerns.
What can cause erectile dysfunction?
How is erectile dysfunction treated?
Which ED treatment could be right for me?
When should I speak to my GP about ED?
Already on treatment? Switch with PillSuite
Erectile dysfunction can affect both confidence and relationships, but with the right medical support, effective treatment is more accessible than ever. Our expert-led programmes provide safe, discreet, and clinically approved solutions tailored to your individual needs and lifestyle.
Medically Approved Treatments
Access trusted prescription treatments designed to help improve blood flow and support stronger, longer-lasting erections when needed.
Discreet and Convenient Care
Receive professional support and treatment from the comfort of your home with a fully online, private, and hassle-free process.
Ongoing Monitoring and Adjustments
Benefit from continued guidance and regular treatment reviews, allowing your plan to be adjusted based on your experience and results.
Why PillSuite
Why Choose PillSuite?
A regulated UK pharmacy, our own clinical team, and treatment decided on your health rather than at a checkout.
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UK-based clinical team
Your consultation is reviewed by our own UK clinical team. Every request is assessed against your full medical history before any treatment is approved.
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Clinically proven treatments, safely prescribed
Our clinical team assesses every treatment request carefully. Where appropriate, we prescribe UK-licensed medicines, which are dispensed by our pharmacy.
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Long-term support
Support does not stop at delivery. Our pharmacy team stays with you throughout treatment, with a focus on results that last.
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Treatment plans personalised to you
No two people are the same. Your plan is built around your health, your goals and how you respond to treatment.
Reviewed by our Clinician.
Every ED treatment request is individually assessed before a prescription is issued. We consider your medical history, current medicines and individual circumstances to make sure treatment is safe and appropriate for you.
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Qualified UK Prescriber
Every treatment request is assessed by a qualified UK prescriber before a prescription is issued.
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Thorough Clinical Assessment
We review relevant health information, eligibility criteria and potential risks before making a prescribing decision. Additional checks may be required.
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Regulated Pharmacy Supply
Medicines are sourced through regulated UK pharmaceutical wholesalers and dispensed by PillSuite Pharmacy.
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Ongoing Clinical Monitoring
Follow-up reviews help us assess your progress, manage potential side effects and determine whether treatment should continue or change.
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Questions, answered.
How do erectile dysfunction tablets work?
Erectile dysfunction tablets such as sildenafil and tadalafil work by increasing blood flow to the penis, helping you achieve and maintain an erection when sexually aroused.
Both medicines belong to a group called PDE5 inhibitors. They help the blood vessels in the penis relax, allowing more blood to flow into the area during sexual stimulation.
These treatments do not automatically cause an erection or increase sexual desire. Sexual stimulation is still needed for them to work.
How quickly do sildenafil and tadalafil work?
Sildenafil is usually taken around one hour before sex and typically starts working within 30 to 60 minutes. Its effects can last for up to four hours.
Tadalafil can start working within 30 minutes and may remain effective for up to 36 hours, offering greater flexibility around timing.
These timeframes can vary between individuals. Both treatments require sexual stimulation to work, and their duration of action does not mean you will have a continuous erection.
Will I be prescribed ED treatment after completing the assessment?
Completing an online assessment does not automatically mean you will receive a prescription.
A qualified UK prescriber will review your symptoms, medical history, current medications and overall health to determine whether ED treatment is safe and suitable for you.
If treatment is appropriate, a prescription may be issued. If further information is needed, we’ll contact you before making a decision.
If treatment isn’t suitable, we’ll explain the next steps and recommend seeking further medical advice where appropriate.
Can I take ED tablets with food or alcohol?
Sildenafil and tadalafil can both be taken with or without food, although a heavy or high-fat meal may delay how quickly sildenafil starts working. Tadalafil is generally not affected by food.
Drinking excessive amounts of alcohol can make it more difficult to achieve an erection and may increase side effects such as dizziness, headaches and low blood pressure.
It’s best to avoid excessive alcohol when taking ED medication. Always follow the instructions provided by your prescriber and the Patient Information Leaflet supplied with your medicine.
Can I take sildenafil or tadalafil with my other medicines?
Sildenafil and tadalafil can interact with certain medicines, so it’s important to tell your prescriber about everything you’re taking before starting treatment.
Important interactions include:
- Nitrates, such as glyceryl trinitrate (GTN) or isosorbide mononitrate, which must not be taken with ED tablets because they can cause a dangerous drop in blood pressure.
- Riociguat, which must not be combined with sildenafil or tadalafil.
- Alpha-blockers and blood pressure medicines, which may increase the risk of dizziness or low blood pressure.
- Certain antibiotics, antifungals and HIV medicines, which can affect how ED treatments work.
You should also tell your prescriber about any supplements or recreational drugs you use, including poppers.
Your prescriber will review your medications and medical history before deciding whether treatment is safe and suitable for you.
What side effects can ED tablets cause?
Like all medicines, sildenafil and tadalafil can cause side effects, although not everyone experiences them. Most are mild and temporary.
Common side effects include:
- Headaches.
- Facial flushing.
- Indigestion or an upset stomach.
- Nasal congestion.
- Dizziness.
Tadalafil may also cause back pain or muscle aches, while sildenafil can occasionally cause temporary changes in vision.
When should I seek medical help?
Stop taking the medication and seek urgent medical advice if you experience sudden changes in vision or hearing.
Seek emergency medical help if you develop chest pain, an erection lasting four hours or longer, or symptoms of a severe allergic reaction.
For further information, refer to the Patient Information Leaflet supplied with your medicine.
What if my ED treatment doesn't work?
ED treatments don’t work the same way for everyone, and it may take a few attempts to understand how your prescribed medication works best for you.
Factors such as timing, food, alcohol, sexual stimulation and your overall health can affect how well treatment works.
If you’re not getting the expected results, contact your prescriber for advice. They can review your response, check whether you’re taking the medication correctly and consider whether a different dose or treatment may be appropriate.
Do not increase your dose or combine ED medications without medical advice.
Will my ED treatment be private and discreet?
Yes. At PillSuite, we understand that discussing erectile dysfunction can feel personal, so your privacy and confidentiality are important to us.
Your online assessment is confidential and reviewed by a qualified UK prescriber. Your personal and medical information is handled securely in accordance with UK data protection requirements.
If treatment is prescribed, your medication will be delivered in plain, discreet packaging without revealing its contents.
Our pharmacy team is also available if you have any questions or concerns about your treatment.
Ready to take the next step?
Start with a confidential online assessment and find out whether erectile dysfunction treatment could be suitable for you.